Identification of novel inhibitors of Mycobacterium smegmatis growth through genome-wide overexpression of Cluster P3 mycobacteriophage Xavia genes

Tennakoon A, Edirisingha IK, Rutledge E, Bhattacharyya A, King E, Moresi M, Lovings A, Yarborough PR, Hoben A, Manns G, Gibson TR Jr, Uddin SMA, Bae Y, Taylor N, Johnson TL, Futral M, Wilson P, Brown J, Arbogast ZL, Brooks A, Ward C, Foxworth C, Nguyen K, Fairchild D, Lemus D, White H, Craft H, Adonis J, Givan K, Valdivia S, Wallace KB, Bent M, Mavrodi D, Heller DM, Rijal R*  ·  *Corresponding author

G3 Genes|Genomics|Genetics. 2026. Accepted

Phosphorylation shapes antigen presentation and immune recognition: mechanistic insights and translational perspectives

Rijal R* and Marques AF*  ·  *Corresponding authors

Front Immunol. 2026. PMID: 42657027

Phosphoproteomic Profiling Reveals Overlapping and Distinct Signaling Pathways in Dictyostelium discoideum in Response to Two Different Chemorepellents

Uddin SZ, Rijal R, Pilling D, Gomer RH

Cells. 2025 PMID: 41511344

Pharmacological inhibition of host pathways enhances macrophage killing of intracellular bacterial pathogens

Rijal R* and Gomer RH  ·  *Corresponding author

Microbiol Spectr. 2025. PMID: 41334932

Two endogenous Dictyostelium discoideumchemorepellents use different mechanisms to induce repulsion

El-Sobky MH, Rijal R, Gomer RH

Proc Natl Acad Sci U S A. 2025 PMID: 40424125

Proteomic Analysis of Dictyostelium discoideum by Mass Spectrometry

Rijal R and Gomer RH

Methods Mol Biol. 2024. PMID: 38954210

PTEN and the PTEN-like phosphatase CnrN have both distinct and overlapping roles in Dictyostelium chemorepulsion pathway

Consalvo KM*, Rijal R*, Beruvides SL, Mitchell R, Beauchemin K, Collins D, Scoggin J, Scott J, and Gomer RH  ·  *equal contributions

J Cell Sci. 2024 PMID: 38940195

Gallein potentiates isoniazid’s ability to suppress Mycobacterium tuberculosis growth

Rijal R* and Gomer RH*  ·  *Corresponding authors

Front Microbiol. 2024 PMID: 38690363

Polyphosphate uses mTOR, pyrophosphate, and Rho GTPase components to potentiate bacterial survival in Dictyostelium

Rahman RJ, Rijal R, Jing S, Chen TA, Ismail I, and Gomer RH

mBio. 2023. PMID: 37754562

Starvation Induces Extracellular Accumulation of Polyphosphate in Dictyostelium discoideum to Inhibit Macropinocytosis, Phagocytosis, and Exocytosis

Rijal R*, Ismail I, Jing S, and Gomer RH  ·  *Corresponding author

Int J Mol Sci. 2023 PMID: 36982997

Dictyostelium discoideum cells retain nutrients when the cells are about to outgrow their food source

Rijal R, Kirolos SA, Rahman RJ, and Gomer RH

J Cell Sci. 2022. PMID: 36017702

Identification of novel proteins in the Dictyostelium discoideum chemorepulsion pathway using REMI

Kirolos SA, Procaccia SR, Groover KE, Das R, Rijal R, and Gomer RH

MicroPubl Biol. 20212 PMID: 35622529

Domain Organization of the UBX Domain Containing Protein 9 and Analysis of Its Interactions With the Homohexameric AAA + ATPase p97 (Valosin-Containing Protein)

Riehl J, Rijal R, Nitz L, Clemen CS, Hofmann A, Eichinger L

Front Cell Dev Biol. 2021. PMID: 34631722

Using Dictyostelium to Develop Therapeutics for Acute Respiratory Distress Syndrome

Kirolos SA, Rijal R, Consalvo KM, Gomer RH

Front Cell Dev Biol. 2021. PMID: 34350188

An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca²⁺

Tang Y, Rijal R, Zimmerhanzel DE, McCullough JR, Cadena LA, Gomer RH

mBio. 2021. PMID: 34154396

Polyphosphate is an extracellular signal that can facilitate bacterial survival in eukaryotic cells

Rijal R, Cadena LA, Smith MR, Carr JF, Gomer RH

Proc Natl Acad Sci U S A. 2020. PMID: 33268492

Functional Characterisation of the Autophagy ATG12~5/16 Complex in Dictyostelium discoideum

Karow M, Fischer S, Meßling S, Konertz R, Riehl J, Xiong Q, Rijal R, Wagle P, Clemen CS, Eichinger L

Cells. 2019. PMID: 32397394

An endogenous chemorepellent directs cell movement by inhibiting pseudopods at one side of cells

Rijal R, Consalvo KM, Lindsey CK, Gomer RH

Mol Biol Cell. 2019. PMID: 30462573

Extracellular signaling in Dictyostelium

Consalvo KM, Rijal R, Tang Y, Kirolos SA, Smith MR, Gomer RH

Int J Dev Biol. 2019. PMID: 31840778

Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum

Fisher S, Rijal R, Frommolt P, Wagle P, Konertz R, Faix J, Meßling S, Eichinger L

Cells. 2019. PMID: 30669443

Expression of N471D strumpellin leads to defects in the endolysosomal system

Song L, Rijal R, Karow M, Stumpf M, Hahn O, Park L, Insall R, Schröder R, Hofmann A, Clemen CS, Eichinger L

Dis Model Mech. 2018. PMID: 30061306.

Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerisation of p97 hexamers

Rijal R, Arhzaouy K, Strucksberg KH, Cross M, Hofmann A, Schröder R, Clemen CS, Eichinger L

Eur J Cell Biol. 2016 . PMID: 27132113